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24.11.2017, 09:27

Cerebrovascular reactivity in patients with chronic renal failure anaemia

Neurologie
Articol din publicatia Timisoara Medical Journal
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Authors: Ligia Petrica1, Maxim Petrica2, Catalin Jianu2, Gheorghe Gluhovschi1,
Adalbert Schiller1, Silvia Velciov1, Virginia Trandafirescu1,
Gheorghe Bozdog1, Cristina Gluhovschi1, Flaviu Bob1

1Dept. of Nephrology, 2Dept. of Neurology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania

Correspondence to:
Ligia Petrica, Dept. of Nephrology, Timisoara
Emergency Clinical Hospital, 156 Dr. I. Bulbuca Blvd., 300736 Timisoara, Romania,Tel. +40-256-463-001
Email: ligiapetrica@yahoo.com

Abstract

Introduction: The cerebrovascular reactivity (CVR) is a haemodynamic parameter which represents the normal increase of the cerebral artery blood flow in response to a vasodilator stimulus, such as hypercapnia. The aim of the study was to assess the CVR by transcranial Doppler (TCD) ultrasound and the breath-holding test (BHT) in patients with chronic renal failure (CRF) anaemia; to correlate the cerebrovascular response to hypercapnia with the severity of anaemia. Material and methods: The study was conducted on a group of 23 patients (p) with pre-dialysis- CRF [divided in 2 subgroups: A- mild anaemia (Hb=8-11g/dl)- 12p; B-severe anaemia (Hb
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